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Migraines and MTHFR

Woman with headache

If you or a family member suffers from migraines it is important to look at the triggers and links for optimal treatment.

A headache can come on at any time and for a number of reasons. However, people who suffer from migraines experience much more complicated symptoms that are often debilitating. Aside from pain, migraines often bring on nausea, vomiting, visual, light and sound sensitivity. Migraines can start as early as 5 years old and can be triggered by foods, stress, hormone changes, chemicals and the environment. A number of studies have implicated genes such as MTHFR in migraine headaches.

Get tested for MTHFR gene mutation.

MTHFR also affects the characteristics of migraine symptoms. One study found that having 2 copies of c677T was associated with migraine with aura and one-sided headache, yet, one copy of c677T was associated with “physical activity and stress as a migraine trigger.” The researchers also found there is tremendous difference in symptoms between men and women. Males with 2 copies of c677T, for example, were more prone to bilateral headaches while the females with one copy of c677T experienced symptoms of nausea and odor aversion more frequently. These studies conclude that there is an overwhelmingly higher incidence of migraine in patients with a MTHFR mutation than without one. If you have a MTHFR mutation, take the right MTHFR supplements.

Other gene SNPs associated with migraine headaches includes MTHFR, KCNK, TRPV, and HCRTR. Yet, MTHFR C677T is the most studied in relation to migraines. When an individual is diagnosed with a vascular type of migraine it is highly correlates with c677T and elevated homocysteine levels. Elevated homocysteine, can inflame the inner lining of the nerves and blood vessels, which can contribute to migraines. Another concern with migraine and MTHFR is the increased incidence of stroke and cardiovascular compilations. Carrying an MTHFR mutation can also predispose the brain to being more sensitive to changes in weather, neurochemical production and have impaired detox capability, all of these can make a brain more sensitive and prone to migraine.

Some easy tips to treat migraine include:

Remember healing takes time, migraine can feel very isolating, get help, get support and get better!!

Get tested for MTHFR gene mutation.

http://www.ncbi.nlm.nih.gov/pubmed/19384265

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